Several U.S. Representatives have announced that they will not seek re-election and many state legislators have made bids for the soon to be vacated seats.
- CD 2 – U.S. Rep. Ted Poe (R-Humble) will not seek re-election. Poe was first elected in 2004 to the 2nd Congressional District.
- CD 3 – U.S. Rep. Sam Johnson (R-Plano) will not seek re-election. Johnson was first elected in 1991 to the 3rd Congressional District.
- CD 5 – U.S. Rep. Jeb Hensarling (R-Dallas), current chairman of the House Finance Services Committee, has also announced he will not seek re-election. Hensarling was first elected in 2002 to the 5th Congressional District.
- CD 16 – U.S. Beto O'Rourke (D-El Paso) is running for the U.S. Senate and will not seek re-election to the 16th Congressional District.
- CD 21 – U.S. Rep. Lamar Smith (R-San Antonio), current chairman of the U.S. House Science, Space and Technology Committee, will not seek re-election. Smith was first elected in 1986 to the 21st Congressional District.
- CD 29 – U.S. Rep. Gene Green (D-Houston) will not seek re-election. Green was first elected in 1992 to the 29th Congressional District.
The following state officeholders have announced potential seat challenges or retirements. Legislators running for open seats are not necessarily retiring.
- HD 4 – Rep. Lance Gooden is running for CD 5.
- HD 8 – Rep. Byron Cook, Chair of House State Affairs, is not seeking re-election.
- HD 13 – Rep. Leighton Schubert is not seeking re-election.
- HD 15 – Rep. Mark Keough, Vice Chair of House International Trade and Intergovernmental Affairs, is seeking county office.
- HD 45 – Rep. Jason Isaac is running for CD 21.
- HD 52 – Rep. Larry Gonzales is not seeking re-election.
- HD 62 – Rep. Larry Phillips, Chair of House Insurance, is not seeking re-election.
- HD 89 – Rep. Jodie Laubenberg, Chair of House Elections, not seeking re-election.
- HD 106 – Rep. Pat Fallon is running for SD 30, currently held by Sen. Craig Estes.
- HD 109 – Rep. Helen Giddings, Vice Chair of House State Affairs, is not seeking re-election.
- HD 113 – Rep. Cindy Burkett is running for SD 2, currently held by Sen. Bob Hall.
- HD 121 – Current Speaker Joe Straus is not seeking re-election.
- HD 126 – Rep. Kevin Roberts is not seeking re-election.
- SD 6 – Sen. Sylvia Garcia is intending to run for CD 29.
- SD 8 – Sen. Van Taylor is intending to run for CD 3.
