The U.S. Environmental Protection Agency released a proposed rule to further protect people from exposure to two chemicals that are toxic, remain in the environment for long periods of time, and accumulate in the body. Both decabromodiphenyl ether (decaBDE) and phenol, isopropylated phosphate (3:1) (PIP (3:1)) are persistent, bioaccumulative and toxic (PBT) chemicals that were subject to risk management rules under the Toxic Substances Control Act (TSCA). EPA’s proposed rule would impose workplace safety protections and restrict water releases. It would also address broader implementation issues affecting the supply chains of various industry sectors including the nuclear energy sector, transportation, construction, agriculture, forestry, mining, life sciences, and semiconductor production.